BRAIN Broad Research in Artificial Intelligence and Neuroscience

Interactive neuro-oncology learning tool

Brain Tumor Symptom Explorer

Explore how tumor location may be associated with psychiatric, cognitive, emotional, and behavioral changes. Select a brain region, review symptom patterns, and test your clinical reasoning.

Open the explorer View study patterns
91patients in the retrospective study
56average age in the full sample
Frontallobes most frequently linked to psychiatric changes
Mood regulation
Impulse control
Social cognition

01 · Interactive atlas

Select a brain region

Click a region on the brain or use the buttons. The information describes associations reported in the study and supporting literature; it does not predict symptoms in an individual patient.

Interactive human brain map in superior view A simplified anatomical superior view. The frontal lobes are anterior, parietal lobes are posterior to the central sulcus, temporal lobes are visible only as narrow lateral portions, and the limbic system is shown as a translucent deep structure.

Tip: use the keyboard to tab through region buttons below.

02 · Study patterns

Regional patterns in the study

The study highlights distinct regional patterns: frontal tumors were most often associated with organic personality and depressive disorders; limbic and temporal involvement was linked with marked behavioral and emotional change; and fronto-parietal locations showed more complex mixed psychiatric presentations.

Most prominent pattern 01

Personality and behavior

Organic personality disorder was the most frequently reported psychiatric manifestation, particularly with left and right frontal tumors.

Women32%
Men29%
Emotional burden 02

Anxiety and depression

Mixed anxiety and depressive disorder was another common pattern, with frontal and fronto-temporal involvement repeatedly represented.

AnxietyDepressionPanic
Clinical context 03

Awareness may be limited

Some patients may not fully recognize personality or behavioral changes, making observations from family and caregivers clinically valuable.

Patient+Caregiver→Clinical team

03 · Knowledge quiz

Check what you learned

Answer questions based only on the information presented in this application. Each answer includes a short explanation.

Question 1 of 6

Question 1

04 · Safe interpretation

When symptoms need attention

Sudden or progressive changes in personality, cognition, emotional control, speech, movement, seizures, or severe headache should be medically assessed. The app cannot determine their cause.

Observe change over time

Record when a symptom began, whether it is new, and how it affects daily functioning.

Useful detail
Onset, duration, frequency
Include another perspective

Family members may notice behavioral or personality changes that the affected person does not recognize.

Useful detail
Examples of changed behavior
Seek professional evaluation

Psychiatric symptoms can have many causes. Neurological and medical assessment helps determine the appropriate next steps.

Purpose
Accurate diagnosis and care