/* =====================================================================
   NeuroCysticercosis AI Atlas  |  companion to a BRAIN narrative review
   Palette and shell mirror the shared BRAIN visual framework.
   ===================================================================== */

:root {
  --burgundy: #700b06;
  --burgundy-dark: #5a0805;
  --bg: #f7ecd0;
  --panel: #ffffff;
  --panel-strong: #fff8e6;
  --ink: #160907;
  --muted: #3f2719;
  --line: #9b6a1f;
  --warning-line: #d99b18;

  --optimal-line: #3aa564;
  --optimal-bg: #eaf6ee;
  --optimal-ink: #1f7a43;
  --warn-bg: #fff4d6;
  --warn-ink: #a5730a;
  --high-line: #c8332a;
  --high-bg: #fbe4e1;
  --high-ink: #8f1108;

  --radius: 14px;
  --radius-sm: 10px;
  --shadow: 0 10px 26px rgba(22, 9, 7, 0.14);
  --shadow-soft: 0 4px 12px rgba(22, 9, 7, 0.08);
}

* { box-sizing: border-box; }

html, body {
  margin: 0;
  padding: 0;
  background: var(--bg);
  color: var(--ink);
  font-family: Arial, Helvetica, sans-serif;
  line-height: 1.55;
}

img { max-width: 100%; display: block; }

/* ===================== Header banner ===================== */
.page-header {
  width: 100%;
  background: var(--burgundy);
  border-bottom: 4px solid var(--warning-line);
}
.image-banner { display: block; }
.image-banner img { width: 100%; height: auto; display: block; }

/* ===================== App shell ===================== */
.app-shell {
  display: grid;
  grid-template-columns: 300px 1fr;
  gap: 26px;
  max-width: 1400px;
  margin: 0 auto;
  padding: 26px;
  align-items: start;
}

/* ===================== Sidebar ===================== */
.sidebar {
  position: sticky;
  top: 20px;
  display: flex;
  flex-direction: column;
  gap: 16px;
  background: linear-gradient(180deg, var(--burgundy) 0%, var(--burgundy-dark) 100%);
  color: #fff8e6;
  border-radius: var(--radius);
  padding: 20px 18px;
  box-shadow: var(--shadow);
}
.brand { display: flex; align-items: center; gap: 12px; }
.brand-mark {
  flex: 0 0 auto;
  width: 44px; height: 44px;
  display: flex; align-items: center; justify-content: center;
  font-size: 24px;
  background: rgba(255, 248, 230, 0.14);
  border: 1px solid rgba(255, 248, 230, 0.35);
  border-radius: 12px;
}
.brand-title { font-weight: 700; font-size: 15.5px; line-height: 1.25; }
.brand-sub { font-size: 12px; opacity: 0.82; margin-top: 2px; }

/* Editable clinician chip */
.patient-chip {
  position: relative;
  background: rgba(255, 248, 230, 0.12);
  border: 1px solid rgba(255, 248, 230, 0.3);
  border-radius: var(--radius-sm);
  padding: 12px 12px 10px;
}
.chip-edit-btn {
  position: absolute; top: 8px; right: 8px;
  width: 26px; height: 26px;
  display: flex; align-items: center; justify-content: center;
  background: rgba(255, 248, 230, 0.16);
  border: 1px solid rgba(255, 248, 230, 0.35);
  border-radius: 8px;
  color: #fff8e6;
  cursor: pointer;
  font-size: 13px;
  transition: background 0.15s ease;
}
.chip-edit-btn:hover { background: rgba(255, 248, 230, 0.3); }
.patient-chip-row { display: flex; justify-content: space-between; align-items: center; gap: 8px; padding: 3px 0; }
.patient-chip-label { font-size: 11.5px; text-transform: uppercase; letter-spacing: 0.04em; opacity: 0.78; }
.patient-chip-value { font-size: 13px; font-weight: 700; text-align: right; }
.chip-tag { background: rgba(255, 248, 230, 0.9); color: var(--burgundy-dark); border-color: transparent; }

.chip-edit-form { display: flex; flex-direction: column; gap: 10px; }
.chip-field { display: flex; flex-direction: column; gap: 5px; font-size: 12px; }
.chip-field input {
  font: inherit;
  padding: 7px 9px;
  border-radius: 8px;
  border: 1px solid rgba(255, 248, 230, 0.5);
  background: #fff8e6;
  color: var(--ink);
}
.chip-edit-actions { display: flex; gap: 8px; }
.chip-save, .chip-cancel {
  flex: 1 1 auto;
  font: inherit;
  font-size: 12.5px;
  font-weight: 700;
  padding: 7px 8px;
  border-radius: 8px;
  cursor: pointer;
  border: 1px solid rgba(255, 248, 230, 0.4);
}
.chip-save { background: #fff8e6; color: var(--burgundy-dark); }
.chip-cancel { background: transparent; color: #fff8e6; }

/* Navigation */
.mobile-nav-label { display: none; font-size: 12px; opacity: 0.85; }
.mobile-nav { display: none; }
.side-nav { display: flex; flex-direction: column; gap: 6px; }
.nav-item {
  display: flex; align-items: center; gap: 10px;
  width: 100%;
  text-align: left;
  font: inherit;
  font-size: 14px;
  color: #fff8e6;
  background: transparent;
  border: 1px solid transparent;
  border-radius: var(--radius-sm);
  padding: 10px 12px;
  cursor: pointer;
  transition: background 0.15s ease, border-color 0.15s ease;
}
.nav-item:hover { background: rgba(255, 248, 230, 0.12); }
.nav-item.is-active { background: rgba(255, 248, 230, 0.2); border-color: rgba(255, 248, 230, 0.4); font-weight: 700; }
.nav-ico { font-size: 16px; width: 20px; text-align: center; }

.ghost-btn {
  font: inherit;
  font-size: 13px;
  font-weight: 700;
  color: #fff8e6;
  background: rgba(255, 248, 230, 0.1);
  border: 1px solid rgba(255, 248, 230, 0.4);
  border-radius: var(--radius-sm);
  padding: 9px 12px;
  cursor: pointer;
  transition: background 0.15s ease;
}
.ghost-btn:hover { background: rgba(255, 248, 230, 0.24); }
.reset-btn { align-self: flex-start; }

.brand-foot { font-size: 11.5px; opacity: 0.78; line-height: 1.5; }
.brand-foot em { font-style: italic; }

/* ===================== Content ===================== */
.content { display: flex; flex-direction: column; gap: 22px; min-width: 0; }

/* Hero */
.hero {
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-left: 6px solid var(--burgundy);
  border-radius: var(--radius);
  padding: 22px 24px;
  box-shadow: var(--shadow-soft);
}
.eyebrow {
  display: inline-block;
  font-size: 12px;
  text-transform: uppercase;
  letter-spacing: 0.08em;
  font-weight: 700;
  color: var(--burgundy);
  background: #fdeede;
  border-radius: 999px;
  padding: 4px 12px;
}
.hero-title { margin: 12px 0 8px; font-size: 27px; color: var(--burgundy-dark); line-height: 1.2; }
.hero-copy { margin: 0; color: var(--muted); font-size: 14.5px; max-width: 74ch; }
.hero-tags { display: flex; flex-wrap: wrap; gap: 8px; margin-top: 14px; }

/* ===================== Modules ===================== */
.module { display: none; flex-direction: column; gap: 22px; }
.module.is-active { display: flex; }
.module:focus { outline: none; }

/* Panels */
.panel-card {
  background: var(--panel);
  border: 1px solid var(--line);
  border-radius: var(--radius);
  padding: 20px 22px;
  box-shadow: var(--shadow-soft);
}
.panel-head { display: flex; align-items: center; justify-content: space-between; gap: 12px; margin-bottom: 12px; flex-wrap: wrap; }
.panel-head h2 { margin: 0; font-size: 18px; color: var(--burgundy-dark); }
.muted-copy { color: var(--muted); font-size: 14px; margin: 0 0 12px; }
.muted-copy:last-child { margin-bottom: 0; }

.two-col { display: grid; grid-template-columns: 1fr 1fr; gap: 22px; align-items: start; }

/* Stat grid */
.stat-grid { display: grid; grid-template-columns: repeat(4, 1fr); gap: 16px; }
.stat-card { display: flex; flex-direction: column; gap: 6px; text-align: left; }
.stat-value { font-size: 30px; font-weight: 800; color: var(--burgundy); line-height: 1; }
.stat-label { font-size: 12.5px; color: var(--muted); }

/* Tags */
.tag {
  display: inline-block;
  font-size: 11.5px;
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.04em;
  color: var(--burgundy-dark);
  background: #fdeede;
  border: 1px solid var(--line);
  border-radius: 999px;
  padding: 4px 11px;
  white-space: nowrap;
}
.tag-soft { background: var(--panel-strong); color: var(--muted); }
.tag-optimal { background: var(--optimal-bg); color: var(--optimal-ink); border-color: var(--optimal-line); }
.tag-warning { background: var(--warn-bg); color: var(--warn-ink); border-color: var(--warning-line); }
.tag-high { background: var(--high-bg); color: var(--high-ink); border-color: var(--high-line); }

/* Alerts */
.alert-box {
  border: 1px solid var(--line);
  border-left: 5px solid var(--warning-line);
  background: var(--panel-strong);
  border-radius: var(--radius-sm);
  padding: 12px 14px;
  font-size: 13.5px;
  color: var(--ink);
  margin-top: 14px;
}
.alert-box strong { color: var(--burgundy-dark); }
.alert-optimal { border-left-color: var(--optimal-line); background: var(--optimal-bg); }
.alert-optimal strong { color: var(--optimal-ink); }
.alert-warning { border-left-color: var(--warning-line); background: var(--warn-bg); }
.alert-warning strong { color: var(--warn-ink); }
.alert-high { border-left-color: var(--high-line); background: var(--high-bg); }
.alert-high strong { color: var(--high-ink); }

/* ===================== Pathogenesis chain ===================== */
.chain-model { display: flex; flex-direction: column; gap: 10px; margin-top: 6px; }
.chain-node {
  position: relative;
  display: flex;
  align-items: flex-start;
  gap: 14px;
  width: 100%;
  text-align: left;
  background: var(--panel);
  border: 1px solid var(--line);
  border-left: 6px solid var(--burgundy);
  border-radius: var(--radius-sm);
  padding: 12px 14px;
  cursor: pointer;
  font: inherit;
  color: var(--ink);
  box-shadow: var(--shadow-soft);
  transition: transform 0.15s ease, box-shadow 0.15s ease, border-color 0.15s ease;
}
.chain-node:hover { transform: translateY(-2px); box-shadow: var(--shadow); }
.chain-node.is-open { border-left-color: var(--warning-line); background: var(--panel-strong); }
.chain-num {
  flex: 0 0 auto;
  width: 30px; height: 30px;
  display: flex; align-items: center; justify-content: center;
  border-radius: 999px;
  background: var(--burgundy);
  color: #fff8e6;
  font-weight: 700;
  font-size: 15px;
}
.chain-body { flex: 1 1 auto; }
.chain-name { display: block; font-weight: 700; font-size: 15px; }
.chain-cue { display: block; font-size: 12.5px; color: var(--muted); margin-top: 2px; }
.chain-more { margin-top: 8px; font-size: 13.5px; color: var(--ink); line-height: 1.5; display: none; }
.chain-node.is-open .chain-more { display: block; }
.chain-caret {
  flex: 0 0 auto;
  width: 22px; height: 22px;
  display: flex; align-items: center; justify-content: center;
  color: var(--burgundy);
  font-size: 16px;
  font-weight: 700;
  margin-top: 3px;
}

/* ===================== Module tile grid ===================== */
.model-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; }
.model-tile {
  text-align: left;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 15px;
  cursor: pointer;
  font: inherit;
  transition: transform 0.12s ease, box-shadow 0.18s ease, border-color 0.18s ease;
}
.model-tile:hover { transform: translateY(-3px); box-shadow: var(--shadow); border-color: var(--burgundy); }
.model-tile .m-ico { font-size: 22px; color: var(--burgundy); }
.model-tile .m-title { font-weight: 700; color: var(--burgundy-dark); margin: 6px 0 4px; }
.model-tile .m-desc { font-size: 12.5px; color: var(--muted); }

/* ===================== Cyst stage track ===================== */
.stage-track { display: grid; grid-template-columns: repeat(4, 1fr); gap: 12px; margin-top: 6px; }
.stage-btn {
  position: relative;
  text-align: left;
  font: inherit;
  cursor: pointer;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-top: 5px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 12px 13px;
  transition: transform 0.12s ease, box-shadow 0.16s ease, border-color 0.16s ease;
}
.stage-btn:hover { transform: translateY(-3px); box-shadow: var(--shadow); }
.stage-btn.is-active { border-color: var(--burgundy); border-top-color: var(--burgundy); background: #fdeede; }
.stage-btn .st-idx { font-size: 11.5px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.04em; color: var(--muted); }
.stage-btn .st-name { display: block; font-weight: 700; font-size: 15px; color: var(--burgundy-dark); margin: 3px 0; }
.stage-btn .st-cue { font-size: 12px; color: var(--muted); }

/* Inflammation meter (shared by stage + region + risk) */
.meter-block { margin: 6px 0 14px; }
.meter-top { display: flex; justify-content: space-between; align-items: baseline; margin-bottom: 5px; }
.meter-label { font-size: 12.5px; font-weight: 700; color: var(--muted); }
.meter-read { font-size: 12.5px; font-weight: 700; color: var(--burgundy-dark); }
.meter-track { height: 12px; border-radius: 999px; background: #efe0c2; border: 1px solid var(--line); overflow: hidden; }
.meter-fill { height: 100%; width: 0; border-radius: 999px; background: var(--burgundy); transition: width 0.4s ease, background 0.3s ease; }
.meter-fill.is-optimal { background: var(--optimal-line); }
.meter-fill.is-warning { background: var(--warning-line); }
.meter-fill.is-high { background: var(--high-line); }

/* Definition detail list */
.detail-list { margin: 0; display: grid; grid-template-columns: 1fr; gap: 10px; }
.detail-list .d-row { border-bottom: 1px dashed var(--line); padding-bottom: 8px; }
.detail-list .d-row:last-child { border-bottom: none; padding-bottom: 0; }
.detail-list dt { font-size: 11.5px; font-weight: 700; text-transform: uppercase; letter-spacing: 0.04em; color: var(--muted); margin-bottom: 2px; }
.detail-list dd { margin: 0; font-size: 13.5px; color: var(--ink); }

/* ===================== Localization ===================== */
.region-list { display: flex; flex-direction: column; gap: 8px; }
.region-btn {
  display: flex; align-items: center; justify-content: space-between; gap: 10px;
  width: 100%;
  text-align: left;
  font: inherit;
  cursor: pointer;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-left: 5px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 10px 13px;
  transition: transform 0.12s ease, border-color 0.16s ease, box-shadow 0.16s ease;
}
.region-btn:hover { transform: translateX(2px); box-shadow: var(--shadow-soft); }
.region-btn.is-active { border-left-color: var(--burgundy); background: #fdeede; }
.region-btn .r-name { font-weight: 700; font-size: 14px; color: var(--burgundy-dark); }
.region-btn .r-lobe { font-size: 12px; color: var(--muted); }

/* Risk profiler */
.risk-viz { display: flex; flex-direction: column; gap: 12px; margin: 8px 0 6px; }
.risk-row { display: grid; grid-template-columns: 150px 1fr 52px; align-items: center; gap: 12px; }
.risk-name { display: flex; flex-direction: column; align-items: flex-start; gap: 3px; font-size: 13px; font-weight: 700; color: var(--muted); }
.risk-name.is-top { color: var(--burgundy-dark); }
.risk-track { height: 14px; border-radius: 999px; background: #efe0c2; border: 1px solid var(--line); overflow: hidden; }
.risk-bar { display: block; height: 100%; width: 0; border-radius: 999px; background: var(--burgundy); transition: width 0.4s ease, background 0.3s ease; }
.risk-bar.is-optimal { background: var(--optimal-line); }
.risk-bar.is-warning { background: var(--warning-line); }
.risk-bar.is-high { background: var(--high-line); }
.risk-score { font-size: 12.5px; font-weight: 700; color: var(--burgundy-dark); text-align: right; }

/* ===================== Imaging ===================== */
.compare-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 14px; }
.compare-col { border: 1px solid var(--line); border-radius: var(--radius-sm); overflow: hidden; }
.compare-col h3 { margin: 0; padding: 10px 13px; font-size: 14px; color: #fff8e6; background: var(--burgundy); }
.compare-col.is-mri h3 { background: var(--burgundy-dark); }
.compare-col ul { margin: 0; padding: 12px 14px 12px 30px; }
.compare-col li { font-size: 13px; color: var(--ink); margin-bottom: 7px; }
.compare-col li:last-child { margin-bottom: 0; }

/* Toggle grids (findings, readiness) */
.toggle-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 10px; margin: 8px 0 4px; }
.toggle-chip {
  display: flex;
  align-items: flex-start;
  gap: 9px;
  padding: 10px 12px;
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  background: var(--panel-strong);
  font-size: 13px;
  color: var(--muted);
  cursor: pointer;
  user-select: none;
  transition: border-color 0.14s ease, background 0.14s ease;
}
.toggle-chip input { width: 16px; height: 16px; margin-top: 2px; accent-color: var(--burgundy); flex: 0 0 auto; }
.toggle-chip .tc-body { display: flex; flex-direction: column; gap: 1px; }
.toggle-chip .tc-name { font-weight: 700; color: var(--ink); }
.toggle-chip .tc-note { font-size: 11.5px; color: var(--muted); }
.toggle-chip.is-on { border-color: var(--burgundy); background: #fdeede; }
.toggle-chip.is-on .tc-name { color: var(--burgundy-dark); }

/* Matcher output */
.match-out { margin-top: 6px; }
.match-modality {
  font-size: 13.5px;
  font-weight: 700;
  color: var(--burgundy-dark);
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 10px 13px;
  margin-bottom: 12px;
}
.rank-viz { display: flex; flex-direction: column; gap: 10px; }
.rank-row { display: grid; grid-template-columns: 168px 1fr 42px; align-items: center; gap: 12px; }
.rank-name { display: flex; flex-direction: column; align-items: flex-start; gap: 3px; font-size: 13px; font-weight: 700; color: var(--muted); }
.rank-lead, .risk-lead { font-size: 9.5px; font-weight: 800; letter-spacing: 0.6px; text-transform: uppercase; color: #fff; background: var(--burgundy); border-radius: 999px; padding: 1px 8px; }
.rank-name.is-top { color: var(--burgundy-dark); }
.rank-track { height: 14px; border-radius: 999px; background: #efe0c2; border: 1px solid var(--line); overflow: hidden; }
.rank-bar { display: block; height: 100%; width: 0; border-radius: 999px; background: var(--line); transition: width 0.4s ease, background 0.3s ease; }
.rank-bar.is-top { background: var(--burgundy); }
.rank-score { font-size: 12.5px; font-weight: 700; color: var(--muted); text-align: right; }

/* ===================== AI toolkit ===================== */
.tool-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 12px; }
.tool-card {
  text-align: left;
  font: inherit;
  cursor: pointer;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 14px 15px;
  transition: transform 0.12s ease, box-shadow 0.16s ease, border-color 0.16s ease;
}
.tool-card:hover { transform: translateY(-3px); box-shadow: var(--shadow); border-color: var(--burgundy); }
.tool-card.is-open { border-color: var(--burgundy); background: #fdeede; }
.tool-top { display: flex; align-items: center; gap: 10px; }
.tool-ico { font-size: 20px; color: var(--burgundy); width: 26px; text-align: center; }
.tool-name { font-weight: 700; font-size: 14.5px; color: var(--burgundy-dark); }
.tool-task { font-size: 12.5px; color: var(--muted); margin-top: 3px; }
.tool-more { font-size: 13px; color: var(--ink); margin-top: 9px; line-height: 1.5; display: none; }
.tool-card.is-open .tool-more { display: block; }

/* Readiness score ring */
.score-block { display: flex; align-items: center; gap: 20px; margin-top: 14px; flex-wrap: wrap; }
.score-ring {
  flex: 0 0 auto;
  width: 118px; height: 118px;
  border-radius: 999px;
  display: flex; align-items: center; justify-content: center;
  background: conic-gradient(var(--line) 0deg, #efe0c2 0deg);
  transition: background 0.4s ease;
}
.score-ring span {
  width: 88px; height: 88px;
  border-radius: 999px;
  background: var(--panel);
  border: 1px solid var(--line);
  display: flex; align-items: center; justify-content: center;
  font-size: 24px; font-weight: 800; color: var(--burgundy-dark);
}
.score-side { flex: 1 1 240px; min-width: 220px; }
.score-caption { font-size: 13.5px; font-weight: 700; color: var(--burgundy-dark); margin-bottom: 2px; }

/* ===================== Case brief ===================== */
.brief-list { display: flex; flex-direction: column; gap: 9px; }
.brief-output {
  min-height: 150px;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 14px 16px;
  font-size: 13.5px;
  color: var(--ink);
  line-height: 1.6;
}
.brief-output p { margin: 0 0 10px; }
.brief-output p:last-child { margin-bottom: 0; }
.brief-output .bo-lead { font-weight: 700; color: var(--burgundy-dark); }
.brief-output .bo-empty { color: var(--muted); font-style: italic; }

.metric-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 12px; margin-top: 14px; }
.metric-card {
  display: flex; flex-direction: column; gap: 6px;
  background: var(--panel-strong);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 12px 14px;
}
.metric-card .mc-val { font-size: 22px; font-weight: 800; color: var(--burgundy); line-height: 1; }
.metric-card .mc-lab { font-size: 12px; color: var(--muted); }

/* ===================== Responsive ===================== */
@media (max-width: 1120px) {
  .app-shell { grid-template-columns: 250px 1fr; gap: 18px; padding: 18px; }
  .stat-grid { grid-template-columns: repeat(2, 1fr); }
  .model-grid { grid-template-columns: repeat(2, 1fr); }
  .stage-track { grid-template-columns: repeat(2, 1fr); }
}

@media (max-width: 820px) {
  .app-shell { grid-template-columns: 1fr; }
  .sidebar { position: static; }
  .side-nav { display: none; }
  .mobile-nav-label { display: block; }
  .mobile-nav {
    display: block;
    width: 100%;
    font: inherit;
    padding: 10px 12px;
    border-radius: var(--radius-sm);
    border: 1px solid rgba(255, 248, 230, 0.5);
    background: #fff8e6;
    color: var(--ink);
  }
  .two-col { grid-template-columns: 1fr; }
  .stat-grid { grid-template-columns: repeat(2, 1fr); }
  .model-grid { grid-template-columns: 1fr; }
  .stage-track { grid-template-columns: 1fr; }
  .compare-grid { grid-template-columns: 1fr; }
  .toggle-grid { grid-template-columns: 1fr; }
  .tool-grid { grid-template-columns: 1fr; }
  .risk-row { grid-template-columns: 116px 1fr 46px; gap: 8px; }
  .rank-row { grid-template-columns: 130px 1fr 40px; gap: 8px; }
  .hero-title { font-size: 23px; }
}

@media (max-width: 520px) {
  .stat-grid { grid-template-columns: 1fr; }
  .metric-grid { grid-template-columns: 1fr; }
  .risk-row { grid-template-columns: 1fr; gap: 4px; }
  .risk-score { text-align: left; }
  .rank-row { grid-template-columns: 1fr; gap: 4px; }
  .rank-score { text-align: left; }
}