BRAIN · AI Knowledge Graph

An Extended Personalised Chemotherapy Response Model Incorporating Inflammation and Individual Variability in Childhood Acute Lymphoblastic Leukemia

Interactive knowledge graph of a personalised 6-mercaptopurine therapy model integrating pharmacokinetics, pharmacodynamics, haematopoietic dynamics, inflammation, nutrition, physical activity, vitamin D, TPMT genetics, virtual-patient simulation, and genetic-algorithm dose optimisation.