Exploring the Neuropsychiatric Dimensions of Psoriasis: Pathophysiology, Clinical Implications, and Integrated Care Approaches

Abstract

Psoriasis is a long-term inflammatory skin disorder that significantly affects a patient's quality of life in addition to having notable physical symptoms. Recent research has increasingly focused on the neuropsychiatric dimensions of psoriasis, recognizing the complex interplay between psychological health and dermatological disease. There is growing recognition of the correlation between psoriasis and neuropsychiatric conditions such as anxiety, depression, and cognitive decline, indicating the reciprocal interaction of the skin and brain. This study explores the prevalence and implications of neuropsychiatric disorders among 3,850 psoriasis patients, of whom 458 were diagnosed with neuropsychiatric conditions. The results emphasize the value of treating psoriasis with a multidisciplinary approach. Integrating care that addresses dermatological and neuropsychiatric health is crucial for improving patient outcomes and quality of life.