BRAIN. Broad Research in Artificial Intelligence and Neuroscience

Volume: 16 | Issue: 4 |

A New Preliminary Model for Studying the Interconnection Between Nutrition and Neuropsychiatric Symptoms: Design and Impact Assessment

Published December 5, 2025
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Lucia Blendea - Grigore T. Popa University of Medicine and Pharmacy, Iasi (RO), Ancuta Andreea Miler - Grigore T. Popa University of Medicine and Pharmacy, Iasi (RO), Malina Visternicu - Ioan Haulica Institute, Apollonia University, Iasi (RO), Ioan Gotca - Grigore T. Popa University of Medicine and Pharmacy, Iasi (RO), Judit Csabai - University of Nyíregyháza, Nyíregyháza (HU), Bogdan Novac - University of Medicine and Pharmacy Grigore T. Popa, Iasi (RO), Otilia Novac - University of Medicine and Pharmacy Grigore T. Popa, Iasi (RO), Anca Trifan - Grigore T. Popa University of Medicine and Pharmacy of Iasi; Institute of Gastroenterology and Hepatology, St. Spiridon University Hospital, Iasi (RO), Daniel Vasile Timofte - Grigore T. Popa University of Medicine and Pharmacy, Iasi (RO),

Abstract

Mental, neurological, and substance use disorders represent a major global problem. In this context, nutrition is crucial as it affects both the severity and incidence of neuropsychiatric symptoms. In addition to drug treatments, lifestyle modifications, including dietary interventions and targeted supplementation with specific nutrients, could have a beneficial effect on various neuropsychiatric disorders. This study introduces a preliminary framework for assessing the link between nutrition and neuropsychiatric symptoms. Thus, the Evaluating the Importance of Nutrition in Neuropsychiatric Manifestations (SENM) Scale provides a structured approach to examine how diet affects mental health. The study sample of 264 participants, including patients diagnosed with depression, anxiety, and bipolar disorder, as well as mental health and nutrition specialists. Preliminary results indicate a significant correlation between nutritional deficiencies (e.g., B vitamins, omega-3) and worsening of symptoms. Also, most participants emphasised integrating nutritional education into neuropsychiatric treatments. The conclusions suggest that nutrition can be an effective adjunct in mental health treatments, with practical applications and promising future directions.


Academic discipline and sub-disciplines: Psychiatry; Neurology; Artificial Intelligence

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DOI: http://dx.doi.org/10.70594/brain/16.4/27

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