Cerebral Oedema in Diabetic Ketoacidosis

Nona Gîrlescu - The Institute of Forensic Medicine, Iasi "Gr. T. Popa" University of Medicine and Pharmacy, Iasi (RO), Iuliana Hunea - The Institute of Forensic Medicine, Iasi "Gr. T. Popa" University of Medicine and Pharmacy, Iasi (RO), Madalina-Maria Diac - The Institute of Forensic Medicine, Iasi, Romania; Department of Forensic Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi (RO), Simona-Irina Damian - Associate Professor PhD, Department of Forensic Medicine, Gr. T. Popa University of Medicine and Pharmacy, Iasi; The Institute of Forensic Medicine, Iasi. (RO), Anton Knieling - The Institute of Forensic Medicine, Iasi, Romania; Department of Forensic Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi (RO), Diana Bulgaru-Iliescu - The Institute of Forensic Medicine, Iasi, Romania; Department of Forensic Medicine, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi (RO),

Abstract


Cerebral oedema in diabetic ketoacidosis (CODKA) is a controversial subject both in medical and forensic practice as well as in the specialized literature, in the light of the non-homogeneous theories regarding the pathophysiological mechanisms. It would seem that the ground of CEDKA would be a combination/fusion of processes that affect both metabolic changes in diabetic ketoacidosis (DKA) and aggressive therapy to combat DKA. This article wants to underline the importance of knowing and deepening the pathophysiological mechanism that leads to the installation of cerebral oedema (CO) in DKA, focusing on the potential of the thanatogenerator mechanism.

Keywords


diabetic ketoacidosis; cerebral oedema; mechanism; death.

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